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Hyperactive Innate Immunity Causes Degeneration of Dopamine Neurons upon Altering Activity of Cdk5

Innate immunity is central to the pathophysiology of neurodegenerative disorders, but it remains unclear why immunity is altered in the disease state and whether changes in immunity are a cause or a consequence of neuronal dysfunction. Here, we identify a molecular pathway that links innate immunity...

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Bibliografiske detaljer
Udgivet i:Cell Rep
Main Authors: Shukla, Arvind Kumar, Spurrier, Joshua, Kuzina, Irina, Giniger, Edward
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6442473/
https://ncbi.nlm.nih.gov/pubmed/30605670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.12.025
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