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Metformin inhibits the type 1 interferon response in human CD4(+) T cells
In systemic lupus erythematosus (SLE), defective clearance of apoptotic debris and activation of innate cells result in a chronically activated type 1 interferon (T1 IFN) response, which can be measured in peripheral blood mononuclear cells (PBMCs) of most patients. Metformin, a widely used prescrip...
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| Publicado no: | J Immunol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6615983/ https://ncbi.nlm.nih.gov/pubmed/31160534 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1801651 |
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