The Major Cholesterol Metabolite Cholestane-3β,5α,6β-Triol Functions as an Endogenous Neuroprotectant

Overstimulation of NMDA-type glutamate receptors is believed to be responsible for neuronal death of the CNS in various disorders, including cerebral and spinal cord ischemia. However, the intrinsic and physiological mechanisms of modulation of these receptors are essentially unknown. Here we report...

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Veröffentlicht in:J Neurosci
Hauptverfasser: Hu, Haiyan, Zhou, Yuehan, Leng, Tiandong, Liu, Ailing, Wang, Youqiong, You, Xiuhua, Chen, Jingkao, Tang, Lipeng, Chen, Wenli, Qiu, Pengxin, Yin, Wei, Huang, Yijun, Zhang, Jingxia, Wang, Liwei, Sang, Hanfei, Yan, Guangmei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6615515/
https://ncbi.nlm.nih.gov/pubmed/25143622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0344-14.2014
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