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The Major Cholesterol Metabolite Cholestane-3β,5α,6β-Triol Functions as an Endogenous Neuroprotectant

Overstimulation of NMDA-type glutamate receptors is believed to be responsible for neuronal death of the CNS in various disorders, including cerebral and spinal cord ischemia. However, the intrinsic and physiological mechanisms of modulation of these receptors are essentially unknown. Here we report...

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Détails bibliographiques
Publié dans:J Neurosci
Auteurs principaux: Hu, Haiyan, Zhou, Yuehan, Leng, Tiandong, Liu, Ailing, Wang, Youqiong, You, Xiuhua, Chen, Jingkao, Tang, Lipeng, Chen, Wenli, Qiu, Pengxin, Yin, Wei, Huang, Yijun, Zhang, Jingxia, Wang, Liwei, Sang, Hanfei, Yan, Guangmei
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6615515/
https://ncbi.nlm.nih.gov/pubmed/25143622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0344-14.2014
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