Cholestane-3β, 5α, 6β-triol Suppresses Proliferation, Migration, and Invasion of Human Prostate Cancer Cells

Oxysterols are oxidation products of cholesterol. Cholestane-3β, 5α, 6β-triol (abbreviated as triol) is one of the most abundant and active oxysterols. Here, we report that triol exhibits anti-cancer activity against human prostate cancer cells. Treatment of cells with triol dose-dependently suppres...

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Huvudupphovsmän: Lin, Ching-Yu, Huo, Chieh, Kuo, Li-Kuo, Hiipakka, Richard A., Jones, Richard Baker, Lin, Hui-Ping, Hung, Yuwen, Su, Liang-Cheng, Tseng, Jen-Chih, Kuo, Ying-Yu, Wang, Yu-Ling, Fukui, Yasuhisa, Kao, Yung-Hsi, Kokontis, John M., Yeh, Chien-Chih, Chen, Linyi, Yang, Shiaw-Der, Fu, Hsiao-Hui, Chen, Ya-Wen, Tsai, Kelvin K. C., Chang, Jang-Yang, Chuu, Chih-Pin
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2013
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3681800/
https://ncbi.nlm.nih.gov/pubmed/23785446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065734
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