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Flubendazole demonstrates valid antitumor effects by inhibiting STAT3 and activating autophagy
BACKGROUND: Signal transducer and activator of transcription 3 (STAT3) is an oncogene, which upregulates in approximately 70% of human cancers. Autophagy is an evolutionarily conserved process which maintains cellular homeostasis and eliminates damaged cellular components. Moreover, the STAT3 signal...
Salvato in:
| Pubblicato in: | J Exp Clin Cancer Res |
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| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6615228/ https://ncbi.nlm.nih.gov/pubmed/31287013 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1303-z |
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