Rhein shows potent efficacy against non-small-cell lung cancer through inhibiting the STAT3 pathway

BACKGROUND: Non-small-cell lung cancer (NSCLC) comprises about 85% of all lung cancers and is usually diagnosed at an advanced stage with poor prognosis. The IL-6/STAT3 signaling pathway plays a pivotal role in NSCLC biology. Rhein is a lipophilic anthraquinone extensively found in medicinal herbs....

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Detalhes bibliográficos
Publicado no:Cancer Manag Res
Main Authors: Yang, Lehe, Li, Jifa, Xu, Lingyuan, Lin, Shichong, Xiang, Youqun, Dai, Xuanxuan, Liang, Guang, Huang, Xiaoying, Zhu, Jiandong, Zhao, Chengguang
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2019
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6362962/
https://ncbi.nlm.nih.gov/pubmed/30774444
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