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Targeting mRNA Decapping in AML
In this issue of Cancer Cell, Yamauchi et al. identify a dependency of acute myeloid leukemia (AML) on DCPS, which catalyzes the final step of 3′-to-5′ mRNA decay and is implicated in numerous aspects of RNA metabolism. DCPS is targetable with a clinical inhibitor, underscoring the translational imp...
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| Publicado en: | Cancer Cell |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6614869/ https://ncbi.nlm.nih.gov/pubmed/29533777 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2018.02.015 |
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