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Single-molecule live cell imaging of Rep reveals the dynamic interplay between an accessory replicative helicase and the replisome

DNA replication must cope with nucleoprotein barriers that impair efficient replisome translocation. Biochemical and genetic studies indicate accessory helicases play essential roles in replication in the presence of nucleoprotein barriers, but how they operate inside the cell is unclear. With high-...

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Détails bibliographiques
Publié dans:Nucleic Acids Res
Auteurs principaux: Syeda, Aisha H, Wollman, Adam J M, Hargreaves, Alex L, Howard, Jamieson A L, Brüning, Jan-Gert, McGlynn, Peter, Leake, Mark C
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6614839/
https://ncbi.nlm.nih.gov/pubmed/31028385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz298
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