Conformational communication mediates the reset step in t(6)A biosynthesis

The universally conserved N(6)-threonylcarbamoyladenosine (t(6)A) modification of tRNA is essential for translational fidelity. In bacteria, t(6)A biosynthesis starts with the TsaC/TsaC2-catalyzed synthesis of the intermediate threonylcarbamoyl adenylate (TC–AMP), followed by transfer of the threony...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Luthra, Amit, Paranagama, Naduni, Swinehart, William, Bayooz, Susan, Phan, Phuc, Quach, Vanessa, Schiffer, Jamie M, Stec, Boguslaw, Iwata-Reuyl, Dirk, Swairjo, Manal A
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Structural Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6614819/
https://ncbi.nlm.nih.gov/pubmed/31114923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz439
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