Rouse model with transient intramolecular contacts on a timescale of seconds recapitulates folding and fluctuation of yeast chromosomes

DNA folding and dynamics along with major nuclear functions are determined by chromosome structural properties, which remain, thus far, elusive in vivo. Here, we combine polymer modeling and single particle tracking experiments to determine the physico-chemical parameters of chromatin in vitro and i...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Socol, Marius, Wang, Renjie, Jost, Daniel, Carrivain, Pascal, Vaillant, Cédric, Le Cam, Eric, Dahirel, Vincent, Normand, Christophe, Bystricky, Kerstin, Victor, Jean-Marc, Gadal, Olivier, Bancaud, Aurélien
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2019
Témata:
Gene regulation, Chromatin and Epigenetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6614813/
https://ncbi.nlm.nih.gov/pubmed/31114898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz374
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