Rouse model with transient intramolecular contacts on a timescale of seconds recapitulates folding and fluctuation of yeast chromosomes

DNA folding and dynamics along with major nuclear functions are determined by chromosome structural properties, which remain, thus far, elusive in vivo. Here, we combine polymer modeling and single particle tracking experiments to determine the physico-chemical parameters of chromatin in vitro and i...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Socol, Marius, Wang, Renjie, Jost, Daniel, Carrivain, Pascal, Vaillant, Cédric, Le Cam, Eric, Dahirel, Vincent, Normand, Christophe, Bystricky, Kerstin, Victor, Jean-Marc, Gadal, Olivier, Bancaud, Aurélien
Format: Artigo
Language:Inglês
Published: Oxford University Press 2019
Subjects:
Gene regulation, Chromatin and Epigenetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6614813/
https://ncbi.nlm.nih.gov/pubmed/31114898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz374
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