Rouse model with transient intramolecular contacts on a timescale of seconds recapitulates folding and fluctuation of yeast chromosomes

DNA folding and dynamics along with major nuclear functions are determined by chromosome structural properties, which remain, thus far, elusive in vivo. Here, we combine polymer modeling and single particle tracking experiments to determine the physico-chemical parameters of chromatin in vitro and i...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Socol, Marius, Wang, Renjie, Jost, Daniel, Carrivain, Pascal, Vaillant, Cédric, Le Cam, Eric, Dahirel, Vincent, Normand, Christophe, Bystricky, Kerstin, Victor, Jean-Marc, Gadal, Olivier, Bancaud, Aurélien
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Gene regulation, Chromatin and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6614813/
https://ncbi.nlm.nih.gov/pubmed/31114898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz374
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