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Single-molecule visualization of the effects of ionic strength and crowding on structure-mediated interactions in supercoiled DNA molecules

DNA unwinding is an important cellular process involved in DNA replication, transcription and repair. In cells, molecular crowding caused by the presence of organelles, proteins, and other molecules affects numerous internal cellular structures. Here, we visualize plasmid DNA unwinding and binding d...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Scott, Shane, Shaheen, Cynthia, McGuinness, Brendon, Metera, Kimberly, Kouzine, Fedor, Levens, David, Benham, Craig J, Leslie, Sabrina
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6614806/
https://ncbi.nlm.nih.gov/pubmed/31106378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz408
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