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The Use of Psoralen Photobinding to Study Transcription-Induced Supercoiling

Proteins manipulating intracellular DNA necessarily impart torsional stress, which redistributes across the DNA. Overtwisting and undertwisting of the double helix result in the manifestation of positive and negative DNA supercoiling. A growing body of evidence indicates that DNA topology is an impo...

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Bibliographic Details
Published in:Methods Mol Biol
Main Authors: Kouzine, Fedor, Baranello, Laura, Levens, David
Format: Artigo
Language:Inglês
Published: 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7433354/
https://ncbi.nlm.nih.gov/pubmed/29177736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-7459-7_7
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