Trimetazidine inhibits cardiac fibrosis by reducing reactive oxygen species and downregulating connective tissue growth factor in streptozotocin-induced diabetic rats

Diabetes may affect myocardial fibrosis through oxidative stress. Trimetazidine (TMZ) is an anti-anginal agent. The present study aimed to determine the modulatory effect of TMZ on reactive oxygen species (ROS) and connective tissue growth factor (CTGF) expression and to evaluate the potential of TM...

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Foilsithe in:Exp Ther Med
Main Authors: Zhao, Yunyue, Li, Suhua, Quan, Enxi, Zhang, Hui, Wu, Yongxiang, Luo, Yanting, Peng, Long, Wang, Jiarui, Zhu, Jieming, Liu, Jinlai
Formáid: Artigo
Teanga:Inglês
Foilsithe: D.A. Spandidos 2019
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Articles
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6614713/
https://ncbi.nlm.nih.gov/pubmed/31363380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2019.7705
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