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A Combined Transcriptomic and Genomic Analysis Identifies a Gene Signature Associated With the Response to Anti-TNF Therapy in Rheumatoid Arthritis

Background: Rheumatoid arthritis (RA) is the most frequent autoimmune disease involving the joints. Although anti-TNF therapies have proven effective in the management of RA, approximately one third of patients do not show a significant clinical response. The objective of this study was to identify...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Aterido, Adrià, Cañete, Juan D., Tornero, Jesús, Blanco, Francisco, Fernández-Gutierrez, Benjamín, Pérez, Carolina, Alperi-López, Mercedes, Olivè, Alex, Corominas, Héctor, Martínez-Taboada, Víctor, González, Isidoro, Fernández-Nebro, Antonio, Erra, Alba, López-Lasanta, María, López Corbeto, Mireia, Palau, Núria, Marsal, Sara, Julià, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6614444/
https://ncbi.nlm.nih.gov/pubmed/31312201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01459
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