Variation at FCGR2A and Functionally Related Genes Is Associated with the Response to Anti-TNF Therapy in Rheumatoid Arthritis

OBJECTIVE: Anti-TNF therapies have been highly efficacious in the management of rheumatoid arthritis (RA), but 25–30% of patients do not show a significant clinical response. There is increasing evidence that genetic variation at the Fc receptor FCGR2A is associated with the response to anti-TNF the...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Avila-Pedretti, Gabriela, Tornero, Jesús, Fernández-Nebro, Antonio, Blanco, Francisco, González-Alvaro, Isidoro, Cañete, Juan D., Maymó, Joan, Alperiz, Mercedes, Fernández-Gutiérrez, Benjamín, Olivé, Alex, Corominas, Héctor, Erra, Alba, Aterido, Adrià, López Lasanta, María, Tortosa, Raül, Julià, Antonio, Marsal, Sara
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4388501/
https://ncbi.nlm.nih.gov/pubmed/25848939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0122088
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