Variation at interleukin-6 receptor gene is associated to joint damage in rheumatoid arthritis

INTRODUCTION: Interleukin-6 (IL-6) cytokine signaling is key in Rheumatoid Arthritis (RA) pathophysiology. Blocking IL-6 receptor (IL6R) has proven to be a highly effective treatment to prevent joint damage. This study was performed to investigate the association between the genetic variation at IL6...

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Publicado no:Arthritis Res Ther
Main Authors: Lopez-Lasanta, Maria, Julià, Antonio, Maymó, Joan, Fernández-Gutierrez, Benjamín, Ureña-Garnica, Inmaculada, Blanco, Francisco J., Cañete, Juan D., Alperi-López, Mercedes, Olivè, Alex, Corominas, Héctor, Tornero, Jesus, Erra, Alba, Almirall, Miriam, Palau, Nuria, Ortiz, Ana, Avila, Gabriela, Rodriguez-Rodriguez, Luis, Alonso, Arnald, Tortosa, Raül, Gonzalez-Alvaro, Isidoro, Marsal, Sara
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4560075/
https://ncbi.nlm.nih.gov/pubmed/26336855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-015-0737-8
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