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Dapagliflozin rescues endoplasmic reticulum stress-mediated cell death
The new type 2 diabetes drug, dapagliflozin, reduces blood glucose levels and body weight by inhibiting sodium glucose transporter 2 (SGLT2) in proximal tubular cells. SGLT2 inhibitors might modulate glucose influx into renal tubular cells, thereby regulating the metabolic conditions that cause endo...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6614429/ https://ncbi.nlm.nih.gov/pubmed/31285506 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-46402-6 |
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