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Human Antimicrobial RNases Inhibit Intracellular Bacterial Growth and Induce Autophagy in Mycobacteria-Infected Macrophages

The development of novel treatment against tuberculosis is a priority global health challenge. Antimicrobial proteins and peptides offer a multifaceted mechanism suitable to fight bacterial resistance. Within the RNaseA superfamily there is a group of highly cationic proteins secreted by innate immu...

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Détails bibliographiques
Publié dans:Front Immunol
Auteurs principaux: Lu, Lu, Arranz-Trullén, Javier, Prats-Ejarque, Guillem, Pulido, David, Bhakta, Sanjib, Boix, Ester
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6614385/
https://ncbi.nlm.nih.gov/pubmed/31312205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01500
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