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Engineering for Success: Approaches to Improve Chimeric Antigen Receptor T Cell Therapy for Solid Tumors

While impressive clinical responses have been observed using chimeric antigen receptor (CAR) T cells targeting CD19+ hematologic malignancies, limited clinical benefit has been observed using CAR T cells for a variety of solid tumors. Results of clinical studies have highlighted several obstacles wh...

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Detalhes bibliográficos
Publicado no:Drugs
Main Authors: Mata, Melinda, Gottschalk, Stephen
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6613829/
https://ncbi.nlm.nih.gov/pubmed/30796733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40265-019-01071-7
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