Translation control of the immune checkpoint in cancer and its therapeutic targeting

Cancer cells develop mechanisms to escape immunosurveillance, among which modulating the expression of immune suppressive messenger RNAs is most well-documented. However, how this is molecularly achieved remains largely unresolved. Here, we develop an in vivo mouse model of liver cancer to study onc...

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Detalhes bibliográficos
Publicado no:Nat Med
Main Authors: Xu, Yichen, Poggio, Mauro, Jin, Hyun Yong, Shi, Zhen, Forester, Craig M., Wang, Ying, Stumpf, Craig R., Xue, Lingru, Devericks, Emily, So, Lomon, Nguyen, Hao G., Griselin, Alice, Gordan, John D., Umetsu, Sarah E, Reich, Siegfried H., Worland, Stephen T., Asthana, Saurabh, Barna, Maria, Webster, Kevin R., Cunningham, John T., Ruggero, Davide
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6613562/
https://ncbi.nlm.nih.gov/pubmed/30643286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41591-018-0321-2
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