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Reciprocal effects of rab7 deletion in activated and neglected T cells

Mouse models lacking proteins essential for autophagosome formation have demonstrated that autophagy plays a critical role in T cell development and activation. To better understand the function of autophagy in quiescent and activated lymphocytes, we have generated a mouse deficient in rab7 selectiv...

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Detalhes bibliográficos
Main Authors: Roy, Saurabh Ghosh, Stevens, Michael W., So, Lomon, Edinger, Aimee L.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3722312/
https://ncbi.nlm.nih.gov/pubmed/23615463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.24468
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