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Rab7 Activation by Growth Factor Withdrawal Contributes to the Induction of Apoptosis
The Rab7 GTPase promotes membrane fusion reactions between late endosomes and lysosomes. In previous studies, we demonstrated that Rab7 inactivation blocks growth factor withdrawal-induced cell death. These results led us to hypothesize that growth factor withdrawal activates Rab7. Here, we show tha...
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| Glavni autori: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The American Society for Cell Biology
2009
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2695791/ https://ncbi.nlm.nih.gov/pubmed/19386765 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-09-0911 |
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