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Peroxynitrite-mediated SIRT1 Inactivation Contributes to Nicotine-induced Arterial Stiffness in Mice
OBJECTIVE―: Inhibition of Sirtuin-1 (SIRT1), a nicotinamide adenine dinucleotide-dependent protein deacetylase, is linked to cigarette smoking-induced arterial stiffness, but the underlying mechanisms remain largely unknown. The aim of the present study was to determine the effects and mechanisms of...
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| Udgivet i: | Arterioscler Thromb Vasc Biol |
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| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6613385/ https://ncbi.nlm.nih.gov/pubmed/31092012 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.118.312346 |
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