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Genome-wide CRISPR screen identifies suppressors of endoplasmic reticulum stress-induced apoptosis
Sensing misfolded proteins in the endoplasmic reticulum (ER), cells initiate the ER stress response and, when overwhelmed, undergo apoptosis. However, little is known about how cells prevent excessive ER stress response and cell death to restore homeostasis. Here, we report the identification and ch...
Tallennettuna:
| Julkaisussa: | Proc Natl Acad Sci U S A |
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| Päätekijät: | , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
National Academy of Sciences
2019
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6613086/ https://ncbi.nlm.nih.gov/pubmed/31213543 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1906275116 |
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