Compartmentalized biosynthesis of mycophenolic acid

Mycophenolic acid (MPA) from filamentous fungi is the first natural product antibiotic to be isolated and crystallized, and a first-line immunosuppressive drug for organ transplantations and autoimmune diseases. However, some key biosynthetic mechanisms of such an old and important molecule have rem...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Zhang, Wei, Du, Lei, Qu, Zepeng, Zhang, Xingwang, Li, Fengwei, Li, Zhong, Qi, Feifei, Wang, Xiao, Jiang, Yuanyuan, Men, Ping, Sun, Jingran, Cao, Shaona, Geng, Ce, Qi, Fengxia, Wan, Xiaobo, Liu, Changning, Li, Shengying
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6613074/
https://ncbi.nlm.nih.gov/pubmed/31209052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1821932116
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