Complete elucidation of the late steps of bafilomycin biosynthesis in Streptomyces lohii

Bafilomycins are an important subgroup of polyketides with diverse biological activities and possible applications as specific inhibitors of vacuolar H(+)-ATPase. However, the general toxicity and structural complexity of bafilomycins present formidable challenges to drug design via chemical modific...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Biol Chem
Prif Awduron: Li, Zhong, Du, Lei, Zhang, Wei, Zhang, Xingwang, Jiang, Yuanyuan, Liu, Kun, Men, Ping, Xu, Huifang, Fortman, Jeffrey L., Sherman, David H., Yu, Bing, Gao, Song, Li, Shengying
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2017
Pynciau:
Microbiology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5409476/
https://ncbi.nlm.nih.gov/pubmed/28292933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.751255
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