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Complete elucidation of the late steps of bafilomycin biosynthesis in Streptomyces lohii

Bafilomycins are an important subgroup of polyketides with diverse biological activities and possible applications as specific inhibitors of vacuolar H(+)-ATPase. However, the general toxicity and structural complexity of bafilomycins present formidable challenges to drug design via chemical modific...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Li, Zhong, Du, Lei, Zhang, Wei, Zhang, Xingwang, Jiang, Yuanyuan, Liu, Kun, Men, Ping, Xu, Huifang, Fortman, Jeffrey L., Sherman, David H., Yu, Bing, Gao, Song, Li, Shengying
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5409476/
https://ncbi.nlm.nih.gov/pubmed/28292933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.751255
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