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Identification of an unexpected shunt pathway product provides new insights into tirandamycin biosynthesis
Tirandamycin K (7), the first linear 7,13;9,13-diseco-tirandamycin derivative, was isolated from the tamI (encoding the TamI P450 monooxygenase) disruption mutant strain (ΔtamI) of marine Streptomyces sp. 307–9. Its chemical structure with relative and absolute configurations was elucidated by a com...
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Publicado no: | Tetrahedron Lett |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5628624/ https://ncbi.nlm.nih.gov/pubmed/28989201 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2016.11.080 |
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