Pathway analysis with genome-wide association study (GWAS) data detected the association of atrial fibrillation with the mTOR signaling pathway

BACKGROUND: Genome-wide association studies (GWAS) have identified numerous loci associated with diseases and traits. However, the elucidation of disease mechanisms followed by drug development has remained a challenge owing to complex gene interactions. We performed pathway analysis with MAGENTA (M...

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Detalhes bibliográficos
Publicado no:Int J Cardiol Heart Vasc
Main Authors: Ebana, Yusuke, Sun, Yihan, Yang, Xiaoxi, Watanabe, Taiju, Makita, Satoru, Ozaki, Kouichi, Tanaka, Toshihiro, Arai, Hirokuni, Furukawa, Tetsushi
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6612921/
https://ncbi.nlm.nih.gov/pubmed/31321287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijcha.2019.100383
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