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TADOSS: computational estimation of tandem domain swap stability

SUMMARY: Proteins with highly similar tandem domains have shown an increased propensity for misfolding and aggregation. Several molecular explanations have been put forward, such as swapping of adjacent domains, but there is a lack of computational tools to systematically analyze them. We present th...

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書目詳細資料
發表在:Bioinformatics
Main Authors: Lafita, Aleix, Tian, Pengfei, Best, Robert B, Bateman, Alex
格式: Artigo
語言:Inglês
出版: Oxford University Press 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6612889/
https://ncbi.nlm.nih.gov/pubmed/30500878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bty974
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