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Statistical compression of protein sequences and inference of marginal probability landscapes over competing alignments using finite state models and Dirichlet priors

The information criterion of minimum message length (MML) provides a powerful statistical framework for inductive reasoning from observed data. We apply MML to the problem of protein sequence comparison using finite state models with Dirichlet distributions. The resulting framework allows us to supe...

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Bibliografiske detaljer
Udgivet i:Bioinformatics
Main Authors: Sumanaweera, Dinithi, Allison, Lloyd, Konagurthu, Arun S
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6612809/
https://ncbi.nlm.nih.gov/pubmed/31510703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btz368
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