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Efficient merging of genome profile alignments

MOTIVATION: Whole-genome alignment (WGA) methods show insufficient scalability toward the generation of large-scale WGAs. Profile alignment-based approaches revolutionized the fields of multiple sequence alignment construction methods by significantly reducing computational complexity and runtime. H...

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Bibliographic Details
Published in:Bioinformatics
Main Authors: Hennig, André, Nieselt, Kay
Format: Artigo
Language:Inglês
Published: Oxford University Press 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6612806/
https://ncbi.nlm.nih.gov/pubmed/31510683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btz377
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