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Learning signaling networks from combinatorial perturbations by exploiting siRNA off-target effects
MOTIVATION: Perturbation experiments constitute the central means to study cellular networks. Several confounding factors complicate computational modeling of signaling networks from this data. First, the technique of RNA interference (RNAi), designed and commonly used to knock-down specific genes,...
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| 發表在: | Bioinformatics |
|---|---|
| Main Authors: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Oxford University Press
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6612802/ https://ncbi.nlm.nih.gov/pubmed/31510678 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btz334 |
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