Depletion of B cells rejuvenates the peripheral B‐cell compartment but is insufficient to restore immune competence in aging

Aging is associated with increasing prevalence and severity of infections caused by a decline in bone marrow (BM) lymphopoiesis and reduced B‐cell repertoire diversity. The current study proposes a strategy to enhance immune responsiveness in aged mice and humans, through rejuvenation of the B linea...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Avivi, Irit, Zisman‐Rozen, Simona, Naor, Shulamit, Dai, Isabelle, Benhamou, David, Shahaf, Gitit, Tabibian‐Keissar, Hilla, Rosenthal, Noemie, Rakovsky, Aviya, Hanna, Ammuri, Shechter, Arik, Peled, Eli, Benyamini, Noam, Dmitrukha, Ekaterina, Barshack, Iris, Mehr, Ramit, Melamed, Doron
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6612643/
https://ncbi.nlm.nih.gov/pubmed/31056853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12959
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados