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Automated cleaning and pre-processing of immunoglobulin gene sequences from high-throughput sequencing

High-throughput sequencing (HTS) yields tens of thousands to millions of sequences that require a large amount of pre-processing work to clean various artifacts. Such cleaning cannot be performed manually. Existing programs are not suitable for immunoglobulin (Ig) genes, which are variable and often...

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Detalhes bibliográficos
Main Authors: Michaeli, Miri, Noga, Hila, Tabibian-Keissar, Hilla, Barshack, Iris, Mehr, Ramit
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3531709/
https://ncbi.nlm.nih.gov/pubmed/23293637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2012.00386
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