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Automated analysis of immunoglobulin genes from high-throughput sequencing: life without a template
BACKGROUND: Immunoglobulin (that is, antibody) and T cell receptor genes are created through somatic gene rearrangement from gene segment libraries. Immunoglobulin genes are further diversified by somatic hypermutation and selection during the immune response. Studying the repertoires of these genes...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3846367/ https://ncbi.nlm.nih.gov/pubmed/23977981 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2043-9113-3-15 |
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