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Automated analysis of immunoglobulin genes from high-throughput sequencing: life without a template

BACKGROUND: Immunoglobulin (that is, antibody) and T cell receptor genes are created through somatic gene rearrangement from gene segment libraries. Immunoglobulin genes are further diversified by somatic hypermutation and selection during the immune response. Studying the repertoires of these genes...

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Detalhes bibliográficos
Main Authors: Michaeli, Miri, Barak, Michal, Hazanov, Lena, Noga, Hila, Mehr, Ramit
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3846367/
https://ncbi.nlm.nih.gov/pubmed/23977981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2043-9113-3-15
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