STING-associated lung disease in mice relies on T cells but not type I interferon

BACKGROUND: Monogenic interferonopathies are thought to be mediated by type I interferon (IFN). For example, a gain-of-function mutation in STING (STING N153S) up-regulates type I IFN-stimulated genes (ISGs) and causes perivascular inflammatory lung disease in mice. The equivalent mutation in humans...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:J Allergy Clin Immunol
Main Authors: Luksch, Hella, Stinson, W. Alexander, Platt, Derek J., Qian, Wei, Kalugotla, Gowri, Miner, Cathrine A., Bennion, Brock G., Gerbaulet, Alexander, Rösen-Wolff, Angela, Miner, Jonathan J.
Formato: Artigo
Idioma:Inglês
Publicado: 2019
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6612314/
https://ncbi.nlm.nih.gov/pubmed/30772497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2019.01.044
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares