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Regulation of sclerostin in glucocorticoid-induced osteoporosis (GIO) in mice and humans

Glucocorticoids (GC) are used for the treatment of inflammatory diseases, including various forms of arthritis. However, their use is limited, amongst others, by adverse effects on bone. The Wnt and bone formation inhibitor sclerostin was recently implicated in the pathogenesis of GC-induced osteopo...

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Détails bibliographiques
Publié dans:Endocr Connect
Auteurs principaux: Thiele, Sylvia, Hannemann, Anke, Winzer, Maria, Baschant, Ulrike, Weidner, Heike, Nauck, Matthias, Thakker, Rajesh V, Bornhäuser, Martin, Hofbauer, Lorenz C, Rauner, Martina
Format: Artigo
Langue:Inglês
Publié: Bioscientifica Ltd 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6612066/
https://ncbi.nlm.nih.gov/pubmed/31234141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/EC-19-0104
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