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Downregulation of Notch Signaling in Kras-Induced Gastric Metaplasia
Activating mutations and amplification of Kras and, more frequently, signatures for Kras activation are noted in stomach cancer. Expression of mutant Kras(G12D) in the mouse gastric mucosa has been shown to induce hyperplasia and metaplasia. However, the mechanisms by which Kras activation leads to...
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| Publicado no: | Neoplasia |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Neoplasia Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6611983/ https://ncbi.nlm.nih.gov/pubmed/31276933 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2019.06.003 |
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