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Loss of Jag1 cooperates with oncogenic Kras to induce pancreatic cystic neoplasms
Notch signaling exerts both oncogenic and tumor-suppressive functions in the pancreas. In this study, deletion of Jag1 in conjunction with oncogenic Kras(G12D) expression in the mouse pancreas induced rapid development of acinar-to-ductal metaplasia and early stage pancreatic intraepithelial neoplas...
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| Publicado en: | Life Sci Alliance |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Life Science Alliance LLC
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7756968/ https://ncbi.nlm.nih.gov/pubmed/33268505 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.201900503 |
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