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Accurate estimation of cell-type composition from gene expression data

The rapid development of single-cell transcriptomic technologies has helped uncover the cellular heterogeneity within cell populations. However, bulk RNA-seq continues to be the main workhorse for quantifying gene expression levels due to technical simplicity and low cost. To most effectively extrac...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Tsoucas, Daphne, Dong, Rui, Chen, Haide, Zhu, Qian, Guo, Guoji, Yuan, Guo-Cheng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6611906/
https://ncbi.nlm.nih.gov/pubmed/31278265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10802-z
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