A practical guide for mutational signature analysis in hematological malignancies

Analysis of mutational signatures is becoming routine in cancer genomics, with implications for pathogenesis, classification, prognosis, and even treatment decisions. However, the field lacks a consensus on analysis and result interpretation. Using whole-genome sequencing of multiple myeloma (MM), c...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Maura, Francesco, Degasperi, Andrea, Nadeu, Ferran, Leongamornlert, Daniel, Davies, Helen, Moore, Luiza, Royo, Romina, Ziccheddu, Bachisio, Puente, Xose S., Avet-Loiseau, Herve, Campbell, Peter J., Nik-Zainal, Serena, Campo, Elias, Munshi, Nikhil, Bolli, Niccolò
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6611883/
https://ncbi.nlm.nih.gov/pubmed/31278357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11037-8
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