Actin stabilizing compounds show specific biological effects due to their binding mode

Actin binding compounds are widely used tools in cell biology. We compare the biological and biochemical effects of miuraenamide A and jasplakinolide, a structurally related prototypic actin stabilizer. Though both compounds have similar effects on cytoskeletal morphology and proliferation, they aff...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Wang, Shuaijun, Crevenna, Alvaro H., Ugur, Ilke, Marion, Antoine, Antes, Iris, Kazmaier, Uli, Hoyer, Maria, Lamb, Don C., Gegenfurtner, Florian, Kliesmete, Zane, Ziegenhain, Christoph, Enard, Wolfgang, Vollmar, Angelika, Zahler, Stefan
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6611809/
https://ncbi.nlm.nih.gov/pubmed/31278311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-46282-w
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