Actin stabilizing compounds show specific biological effects due to their binding mode

Actin binding compounds are widely used tools in cell biology. We compare the biological and biochemical effects of miuraenamide A and jasplakinolide, a structurally related prototypic actin stabilizer. Though both compounds have similar effects on cytoskeletal morphology and proliferation, they aff...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Wang, Shuaijun, Crevenna, Alvaro H., Ugur, Ilke, Marion, Antoine, Antes, Iris, Kazmaier, Uli, Hoyer, Maria, Lamb, Don C., Gegenfurtner, Florian, Kliesmete, Zane, Ziegenhain, Christoph, Enard, Wolfgang, Vollmar, Angelika, Zahler, Stefan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6611809/
https://ncbi.nlm.nih.gov/pubmed/31278311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-46282-w
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