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Actin stabilizing compounds show specific biological effects due to their binding mode

Actin binding compounds are widely used tools in cell biology. We compare the biological and biochemical effects of miuraenamide A and jasplakinolide, a structurally related prototypic actin stabilizer. Though both compounds have similar effects on cytoskeletal morphology and proliferation, they aff...

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Foilsithe in:Sci Rep
Main Authors: Wang, Shuaijun, Crevenna, Alvaro H., Ugur, Ilke, Marion, Antoine, Antes, Iris, Kazmaier, Uli, Hoyer, Maria, Lamb, Don C., Gegenfurtner, Florian, Kliesmete, Zane, Ziegenhain, Christoph, Enard, Wolfgang, Vollmar, Angelika, Zahler, Stefan
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6611809/
https://ncbi.nlm.nih.gov/pubmed/31278311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-46282-w
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