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High-level expression of biologically active human follicle stimulating hormone in the Chinese hamster ovary cell line by a pair of tricistronic and monocistronic vectors

Recombinant human follicle stimulating hormone (FSH), produced in Chinese hamster ovary (CHO) cells, is widely used for treatment of fertility disorders and is subject to biosimilars development. Cell lines with high specific productivities may simplify the FSH production process. Here, we used our...

詳細記述

保存先:
書誌詳細
出版年:PLoS One
主要な著者: Orlova, Nadezhda A., Kovnir, Sergey V., Khodak, Yulia A., Polzikov, Mikhail A., Nikitina, Victoria A., Skryabin, Konstantin G., Vorobiev, Ivan I.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6611665/
https://ncbi.nlm.nih.gov/pubmed/31276557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0219434
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