Rapamycin Rescues Age-Related Changes in Muscle-Derived Stem/Progenitor Cells from Progeroid Mice

Aging-related loss of adult stem cell function contributes to impaired tissue regeneration. Mice deficient in zinc metalloproteinase STE24 (Zmpste24(−/−)) exhibit premature age-related musculoskeletal pathologies similar to those observed in children with Hutchinson-Gilford progeria syndrome (HGPS)....

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Detaylı Bibliyografya
Yayımlandı:Mol Ther Methods Clin Dev
Asıl Yazarlar: Kawakami, Yohei, Hambright, William S., Takayama, Koji, Mu, Xiaodong, Lu, Aiping, Cummins, James H., Matsumoto, Tomoyuki, Yurube, Takashi, Kuroda, Ryosuke, Kurosaka, Masahiro, Fu, Freddie H., Robbins, Paul D., Niedernhofer, Laura J., Huard, Johnny
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Gene & Cell Therapy 2019
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6610712/
https://ncbi.nlm.nih.gov/pubmed/31312666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2019.05.011
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