HBx-K130M/V131I promotes liver cancer in transgenic mice via AKT/FOXO1 signaling pathway and arachidonic acid metabolism

Chronic hepatitis B viral (HBV) infection remains a high underlying cause for hepatocellular carcinoma (HCC) worldwide, while the genetic mechanisms behind this remain unclear. This study elucidated the mechanisms contributing to tumor development induced by the HBV X (HBx) gene of predominantly Asi...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Mol Cancer Res
Auteurs principaux: Chiu, Amy P, Tschida, Barbara R, Sham, Tung-Ting, Lo, Lilian H, Moriarity, Branden S, Li, Xiao-Xiao, Lo, Regina C, Hinton, David E, Rowlands, Dewi K, Chan, Chi-On, Kam-wah Mok, Daniel, Largaespada, David A, Warner, Nadia, Keng, Vincent W
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6610579/
https://ncbi.nlm.nih.gov/pubmed/30975706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-18-1127
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires