HBx-K130M/V131I promotes liver cancer in transgenic mice via AKT/FOXO1 signaling pathway and arachidonic acid metabolism

Chronic hepatitis B viral (HBV) infection remains a high underlying cause for hepatocellular carcinoma (HCC) worldwide, while the genetic mechanisms behind this remain unclear. This study elucidated the mechanisms contributing to tumor development induced by the HBV X (HBx) gene of predominantly Asi...

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Publicado en:Mol Cancer Res
Main Authors: Chiu, Amy P, Tschida, Barbara R, Sham, Tung-Ting, Lo, Lilian H, Moriarity, Branden S, Li, Xiao-Xiao, Lo, Regina C, Hinton, David E, Rowlands, Dewi K, Chan, Chi-On, Kam-wah Mok, Daniel, Largaespada, David A, Warner, Nadia, Keng, Vincent W
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6610579/
https://ncbi.nlm.nih.gov/pubmed/30975706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-18-1127
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